Faculty grant recipients

The latest grants received by our faculty members

Our faculty members receive research funding from various sources. This page, updated monthly, highlights the latest grants faculty have received to support their work.

Faculty members can submit grants to be included in this list using our online grant reporting form.

Grants Reported in September 2022

Personalized Genetic Drug Technologies and Medical Economies in Canada: Moral Experiment or Curative Renaissance?

SSHRC and Genome Canada

Other contributors

A. Hay, LG. Balneaves, K. Chan, K. O’Doherty, J. Bramson, H. Llewellyn, V. MacDonald, J. Needham, S. Peacock, S. Sundquist

Total funding: $199,462

April 2022 - March 2026

Common language for intimate partner violence risk appraisal and mitigation: An evidence-based policing approach

Social Science and Humanities Research Council

Partnering with police services and universities in Alberta, New Brunswick, and Ontario to study and share evidence-based approaches for assessing risk of intimate partner violence and coercive control.

Total funding: $199,583

2022-2024

What do New Practitioners Need from Continuing Professional Development (CPD): A Case Study of Transition to Practice and Early Career Psychiatrists

CPD Advancement and Ideas Grants - Temerty Faculty of Medicine

The Royal College has stipulated new training experiences (e.g. learning the business aspects of practice, avoiding College complaints, engaging in QI initiatives amongst others) for Psychiatry residents in the penultimate stage of training: Transition to Practice (TTP). We seek to determine gaps in these competencies, as identified by senior Psychiatry residents and Early Career Psychiatrists, which would then inform Continuing Professional Development education sessions in order to best address their needs.

Other faculty contributors

Co-Investigators: Dr. Certina Ho  

Collaborator, representing Early Career Psychiatrists: Dr. Tracey Sarmiento 

Collaborator, representing Equity and Mentorship: Dr. Mary Jane Esplen

Project Advisor: Dr. Sanjeev Sockalingam  

Total funding amount: $5,000

More grants received by faculty members in 2022

A Data Driven Approach to Personalize Psychosocial Treatment for Parents of Children with Disruptive Behaviour Disorder

Canadian Institutes of Health Research (CIHR)

This project will identify which subgroups of parents, and children with emotional and behavioural challenges, benefit most and least from evidence-based psychosocial treatment in order to develop more targeted and personalized interventions.

Other faculty contributors

Co-Investigators: Daniel Gorman, Jennifer Jenkins, Yuanyuan Jiang, Stefan Kloiber, Azadeh Kushki, Judith Laposa, Robert Mcmahon, Marcos Sanches, Debbie Schachter

Total funding (Direct costs): $100,000

July 2022

Dr. Mahavir Agarwal

Dr. Mahavir Agarwal

Is brain insulin resistance a feature of the biology of depression? A pilot multi-modality neuroimaging study in adolescents

Banting and Best Diabetes Centre, University of Toronto

In this study, we will examine whether adolescents with MDD have greater brain insulin resistance compared to age-, sex- and weight-matched healthy controls, and if this predicts clinical, cognitive, and metabolic outcomes at 6 months. 

Other faculty contributors

Co-Investigators: Daphne Korczak, Ariel Graff-Guerrero, Margaret Hahn, Sofia Chavez, Gary Remington

Total funding (Direct costs): $90,000

July 2022 - June 2024

Neurobiological Mechanisms of Reading Disabilities

Canadian Institutes of Health Research (CIHR)

Study incorporates neuroimaging of children with reading disabilities and the characterization of stem cell derived neurons from the children. 

Other faculty contributors

Co-Investigator: Shreejoy Tripathy

Total funding (Direct costs): $1,185,750

April 1, 2022

An adapted early warning signs and symptoms (EWSS) intervention to improve early recognition and referral of childhood cancers in Kenya and Cameroon: An Effectiveness Implementation Study

Canadian Institutes of Health Research (CIHR)

Our overarching aim is to generate robust evidence of the feasibility, effectiveness, and costs related to implementing an adapted Early Warning Signs and Symptoms (EWSS) intervention in Cameroon and Kenya. We will address the study aims through five linked objectives: 1) Adapt core intervention components; 2) Identify barriers and facilitators; 3) Execute the intervention; 4) Evaluate clinical effectiveness; 5) Evaluate implementation effectiveness.

Other contributors

Primary Named Applicant and Co-Principal Investigator: Avram Denburg

Co-Principal Investigator: Sumit Gupta

Total funding (Direct costs): $1,250,776

Oct 2022

Implementing a sudden cardiac death risk assessment tool in childhood hypertrophic cardiomyopathy

Canadian Institutes of Health Research (CIHR)

The major goals of this project are to utilize implementation science methods to implement PRIMaCY, a sudden death risk prediction tool for childhood HCM, within hospital EHRs and workflows using an organization and physician focused implementation strategy; and to assess implementation outcomes and identify and address implementation barriers and facilitators to improve the effectiveness of the implementation approach.

Other contributors

Primary Named Applicant and Co-Principal Investigator: Seema Mital

Total funding (Direct costs): $631,126

Oct 2022

STS, Disability Arts, and the Frictions of Futurity in Transplant Medicine: A Multidisciplinary Salon 

Social Sciences and Humanities Research Council (SSHRC)

This SSHRC Connection Grant will support the collaboration of international artists and scholars through two multidiscplinary salons. The salons will use arts-based research methods and practices to examine novel ways of understanding psychosocial challenges that span the solid organ transplantation process. 

Other faculty contributors

Co-Principal Investigators: Kelly Fritsch, Margrit Shildrick

Co-Investigators: Susan Abbey, Donna Stewart

Project collaborator  Kathleen Sheehan, Josee Lynch, Eva-Marie Stern

Total funding (Direct costs): $30,060

March 2022 - March 2023

Temporalities of Cure in Liver Transplantation

University of Toronto Critical Digital Humanities Institute

The "Temporalities" project examines the experience of long-term survivors of liver transplantation, exploring the limitations that surround conceptualizations of survivors’ experiences in biomedical settings and what is lacking in conventional approaches to psychosocial supports for this population. This grant will support a project graduate student to lead a critical discourse analysis of liver transplantation patient manuals along with a series of qualitative interviews and digital storytelling workshops for transplant recipients.

Other faculty contributors

Co-Principal Investigators: Chloe Wong-Mersereau

Total funding (Direct costs): $10,000

April 2022 - August 2022

Functional Electrical Stimulation for Major Depressive Disorder: A Pilot Randomized Controlled Trial

Canadian Institutes of Health Research (CIHR)

Functional Electrical Stimulation of Facial Muscles: Treating Depression with a Smile 

Other faculty contributors

Co-Principal Investigators: Sidney Kennedy, Milos Popovic

Co-Investigators: Benoit H Mulsant

Total funding (Direct costs): $390,000

Oct 2022 - Sept 2025

Feasibility of Inhaled Nitrous Oxide versus Intravenous Ketamine in Treatment-Resistant Depression with Suicidal Ideation: A Pilot Randomized Controlled Trial

American Foundation for Suicide Prevention (AFSP)

This pilot trial will compare inhaled nitrous oxide to IV ketamine for reduction of suicidal ideation in treatment-resistant depression.

Other faculty contributors

Co-Principal Investigators: Sidney Kennedy

Co-Investigators: Ishrat Husain, Benoit H Mulsant

Total funding (Direct costs): $90,000

Oct 2022 - Sept 2024

Understanding attitudes and beliefs toward the COVID-19 vaccines among youth with mental illness

Canadian Institutes of Health Research (CIHR)

The overall objective of this project is to explore the beliefs, attitudes, and information needs of youth with mental illness related to COVID-19 vaccines. Our findings will lead to the co-creation of targeted resources that can support youth, clinicians, and public health professionals in having effective youth-centric discussions about vaccines, mental health, and COVID-19 more generally.

Other faculty contributors

Co-Principal Investigators: Sanjeev Sockalingam, Joanna Henderson, Nicole Kozloff, Andrea Levenson

Total funding (Direct costs): $143,428

December 2022 - December 2023

Physiological Signature of Emotional Distress in Persons with Dementia: Multi-sensory X deep learning to Facilitate Personalized Management of agitation

Canadian Consortium on Neurodegeneration in Aging/CIHR

This project will investigate the physiological signature for "emotional distress" in patients with agitation due to Alzheimer disease leveraging two large multi-centre therapeutic trials. Methodology will include multi-sensory devices and deep learning.

Other faculty contributors

Co-investigators: Krista Lanctot, Tarek Rajji, Corinne Fischer, Andrea Iaboni, and  Sanjeev Kumar.

Total funding (direct costs): $40,000

May 2022 - April 2024

Anti-Muslim Discrimination in Medical Training: The experiences of resident physicians

Education Development Fund

This is a mixed-methods study using quantitative and qualitative methods to quantify and characterize anti-Muslim discrimination in residency training. A survey will be conducted nationally, along with in-depth qualitative interviews to understand the emotional and behavioural impact of discrimination on resident physicians.

Other faculty contributors

Co-Principal Investigators: Susan Abbey, Hashim Khan, Arfeen Malick, Umberin Najeeb, Javeed Sukhera, Juveria Zaheer

Senior advisors: Juveria Zaheer and Susan Abbey

Total funding (Direct costs): $20,000

August 2022

A proof-of-concept randomized controlled trial to show that the antidepressant effects of psilocybin do not require psychedelic effects

Canadian Institutes of Health Research (CIHR)

This proof-of-concept “double dummy” RCT aims to assess whether psilocybin’s antidepressant effects are induced by 5HT2A receptor agonism (and hence by psychedelic effects) in 60 participants with treatment-resistant depression.

Other contributors

Co-Investigators: Daniel Blumberger, David Castle, Stefan Kloiber, Abigail Ortiz, Benoit Mulsant, Joshua Rosenblat, Wei Wang

Total funding (Direct costs): $546,976

Oct 2022 - Sept 2023

The Canadian Mental Health, Equity, and Climate Change Initiative

McConnell Foundation

This knowledge mobilization initiative was developed to enhance Canada's capacity to decrease the mental health impacts of climate change, emphasizing preventative responses for populations experiencing poverty. Subpopulations of focus include women, children and the elderly, and persons lacking adequate housing.

Other contributors

Co-Principal Investigators: Kwame McKenzie, Arun Ravindran, Vicky Stergiopoulos, Samantha Wells, Trevor Young

Total funding (Direct costs): $443,880

June 2022 – June 2025

App for Independence-O (A4i-O) – Expanding a Validated Platform for Complex Behavioral Health to Address Opioid Use

CAMH Foundation

This study involves modifying a digital health platform currently tailored for psychosis to meet the needs of individuals.

Other faculty contributors

o-Investigators: Lena Quilty, David Castle, Tony George, Matthew Sloan, Peter Selby, Jessica D’Arcey

Total funding (direct costs): $165,000

March 2022 - April 2024

Creating an Evidence-Informed, Accessible, Clinically Useful and Personalized Virtual Mental Health Support Framework for School-Age Children on the Autism Spectrum: Building from Pandemic e-Support Experiences

Canadian Institutes of Health Research (CIHR)

This project will provide critical knowledge to create a child- and family-centered e-MH framework for Canadian school-age autistic children and their families. This e-MH framework can be applied widely to enhance personalized support for autistic children across geographical regions and contexts.

Other faculty contributors

Co-Investigator: Stephanie Ameis

Total funding (Direct costs): $657,900

April 2022 - March 2026

rTMS for apathy in dementia: a pilot study

Canadian Institutes of Health Research (CIHR)

Evaluating the effectiveness of rTMS for apathy associated with dementia.

Other faculty contributors

Co-Investigators: D Gallagher, P Giacobbe, N Herrmann, S Nestor, M Rapoport, S Tumat

Total funding (Direct costs): $100,000

Apr 2022 - Mar 2023

Exercise augmenting cognition tDCS (EXACT) trial: A pilot study of a combined exercise and transcranial direct current stimulation intervention for cognition

Canadian Institutes of Health Research (CIHR)

The aim of this study is to assess the efficacy of exercise combined with transcranial direct current stimulation (tDCS) for improving cognition in mild Alzheimer's disease patients. This study may identify a safe, non-invasive treatment approach that preserves cognition in early Alzheimer's disease, therefore having major health implications.

Other contributors

Co-Principal Investigators: Damien Gallagher, Nathan Herrmann

Damien Gallagher, Mark Rapoport and Nathan Herrmann will oversee patient management and care.  Ana Andreazza will perform biomarker analysis. Tarek Rajji will assist with aspects related to the tDCS machines and training.

Total funding (Direct costs): $456,706

Oct 2022 - Sept 2025

Lithium for the Treatment of Paediatric Bipolar Disorder: A Delphi Study

Pooler Charitable Trust, TD Bank

This study will use the Delphi Method to conduct a survey of international experts on the safe and effective use of lithium for the treatment of paediatric bipolar disorder in all phases of illness. 

Other faculty contributors

Co-Principal Investigator: Simina Toma Co-Investigator: Ayal Schaffer

Total funding (Direct costs): $21,850

March 1 2022 - March 1 2023 

Self-Harm Presentations Encountering ED in Youth (SPEEDY): Rapid Risk Stratification for Clinical Management 

American Foundation of Suicide Prevention (AFSP); Young Investigators Grant Competition 

To determine how self-harm method impacts risk of suicide and related outcomes following a first presentation of self-harm to the emergency department for youth. The specific focus will be on cutting versus poisoning as these methods represent over 90% of all emergency room presentations for self-harm among youth.  

Other contributors

Co-Investigators: Kathleen Dobson, Benjamin Goldstein, Nicole Kozloff, Natasha Saunders, Ayal Schaffer, Mark Sinyor (Young Investigator Mentor), Simone Vigod

Total funding (Direct costs):$90,000

Oct 2022 - 2024 

Magnetic Seizure Therapy for Schizophrenia - Neurocircuitry (MAST-Neuro)

Brain and Behavior Research Foundation (NARSAD)

The overarching goal of MAST-Neuro is to identify brain imaging biomarkers that relate to the therapeutic effects and cognitive side effects of MST and ECT. Identifying such brain imaging biomarkers is an important step towards precision medicine, in which targeted treatments may help maximize benefit and minimize risk.

Other faculty contributors

Daniel Blumberger, Co-I for MAST-Neuro, PI for MAST-Trial

George Foussias, Co-I for MAST-Neuro, Co-PI for MAST-Trial

Total funding (Direct costs): $70,000

July 2022 - June 2024

Predicting cardiovascular risk in patients diagnosed with bipolar disorder using clinical and biomarker data: focus on sex-related differences

Canadian Institutes of Health Research (CIHR)

The overall objective of this work is to understand the determinants of sex-related differences in cardiovascular morbidity in bipolar disorder (BD) towards the goal of developing prediction tools that will support prevention. This approach builds on the preliminary work of an interdisciplinary team of junior and senior investigators on: (i) clinical trajectories in BD; (ii) feasibility of using passive sensing in adults with BD during different types of episodes; (iii) cardiovascular morbidity and mortality in BD; (iv) and molecular and genetic basis of BD.

Other faculty contributors

Co-Investigators: Dr. Benjamin Goldstein, Dr. Daniel Felsky, Dr. Ishrat Husein, Mr. Marcos Sanches, Dr. Benoit Mulsant

Total funding (Direct costs): $283,051

April 2022 - March 2025

Dr. Abigail Ortiz

Dr, Abigail Ortiz

Community-based, technology-enabled prediction of post-discharge suicidal behavior in bipolar disorders using passive sensing and pattern recognition

Department of Psychiatry Suicide Studies Fund

This study aims to develop new data modeling to examine changes within each individual, over time, to predict post-discharge suicidal behavior in patients with bipolar disorder.  

Other faculty contributors

Co-applicants: Dr. Daniel Blumberger, Dr. Ishrat Husain, Dr. Juveria Zaheer

Mentor: Dr. Benoit Mulsant

Total funding (Direct costs): $48,000

July 2022 - June 2023

Optimization of Prefrontal Theta-Burst Stimulation to Treat Depression: A Bench to First-in-Human Study

Brain Canada

In this project, we will first optimize theta-burst stimulation to induce plasticity in the prefrontal cortex of an animal model for depression then adapt the preclinical changes to human theta-burst stimulation and compare its ability to induce plasticity in humans compared to traditional protocol. Throughout the project we will also implement integrated Knowledge Translation in partnership with individuals with lived experience, learner and community of practice stakeholders.

Other faculty contributors

Co-Investigators: Branka Agic, Daniel Blumberger, Clement Ma, Benoit Mulsant
Co-Applicants: Graham Collingridge, Evelyn Lambe, Sanjeev Sockalingam

Total funding (Direct costs): $950,000

January 2022 - December 2024

Neurobiological Effects of Psilocybin in Treatment Resistant Bipolar Depression: An Emotional-Processing fMRI Pilot Study

Labatt Family Innovation Fund in Brain Health

We propose an open-label, single-arm, pilot study, wherein twenty participants with moderate to severe treatment resistant bipolar depression (TRBD) will receive one 25 mg dose of oral psilocybin with supportive psychotherapy. Our primary objective is to determine if increased amygdala activity during emotional stimuli post-psilocybin treatment is associated with antidepressant effects in individuals with TRBD.

Other faculty contributors

Mentor: Roger S. McIntyre, MD, FRCPC

Co-Applicants: Ishrat Husain, MBBS, MD(Res.), MRCPsych, Colin Hawco, PhD, Rodrigo Mansur, MD, PhD, David Castle, MD, Hilary Offman, MD, FRCPC,  Wei Wang, PhD

Total funding (Direct costs): $340,000

February 2022 - January 2025

Maintenance Ketamine Infusions for Treatment-Resistant Bipolar Depression: An Open-Label Extension Trial

Physician Service Inc (PSI)

This study will evaluate the mood stabilizing and antidepressant effects of ketamine infusions in bipolar I/II disorder. This study is an add on study to Dr. Rosenblat's CIHR-funded RCT evaluating the acute antidepressant effects of ketamine for bipolar depression. The present study will provide additional 'booster' infusions to ketamine-responders to evaluate if the benefits may be sustained by additional ketamine doses.

Other faculty contributors

Co-investigator: Dr. Rodrigo Mansur

Mentor: Dr. Roger McIntyre

Total funding (Direct costs): $300,000

March 1, 2022 - March 1, 2025

Development of an education module to improve communication, engagement and inclusivity at PM: A curriculum focused on pronouns, gender, sexual orientation and relationship diversity in cancer care

UHN Cancer Experience Program at Princess Margaret

The purpose of this project is to promote knowledge about the health needs of sexual and gender minorities among healthcare providers, administrative/clerical staff and trainees in a format that is inclusive, interactive and effective.

Other faculty contributors

Co-Investigators: Gilla Shapiro, Jennifer Croke

Total funding (Direct costs): $20,000

Lived experience of involuntary transport under the Ontario Mental Health Act: A qualitative study to inform the discussion on non-police responses to mental health crises

Innovation Fund, St. Michael's Hospital Association

This study will evaluate the lived experience of patients who have been apprehended by the police under a Form 1 and investigate the preferences of service users for an alternative authority they may respond to under a Form 1, if at all.

Other faculty contributors

Co-Investigators: Michaela Beder, Amy Gajaria, Samuel Law

Total funding (Direct costs): $22,100

Implementation of Caring Contacts using patient feedback to reduce suicide-related outcomes following psychiatric hospitalization: A community-hospital partnership

The Cass Family Grants for Catalyzing Access and Change and the Healthcare Insurance Reciprocal of Canada (HIROC) Patient Safety Grant

Sunnybrook Department of Psychiatry piloted the first Canadian Caring Contact RCT with some early evidence of success. This project seeks additional patient input to enhance the acceptability and effectiveness of the intervention to reduce suicide-related outcomes. This quality improvement project aims to adapt and improve an evidence-based suicide-prevention initiative for psychiatric inpatients at high risk of suicide following discharge from hospital.

Other contributors

Co-Principal Investigators: Saulo Castel, Ayal Schaffer, Mark Sinyor, Ari Zaretsky

Total funding (Direct costs): $25,000

July 2022 - June 2023

A Psychosocial Transitional Group to Improve Adaptation, Coping and Mental Health Outcomes Following Trauma, Catalyst Grant – Addressing Musculoskeletal

Canadian Institutes of Health Research (CIHR)

A feasibility RCT to test the effectiveness of a psychosocial transitional inpatient group in neuro-musculoskeletal (NMSK) trauma rehabilitation patients to enhance coping, adaptation and self-efficacy and to decrease psychological distress.

Other faculty contributors

Co-Investigators in psychiatry: Janet Ellis Others:  Godleski M, Gotlib Conn L, Guilcher SJT, Hitzig SL, Mayo AL, Redelmeier D, Simpson R, Wasilewski M. (Rehab/Physiatry)   Knowledge User: Domingo A

Total funding (Direct costs): $99,986

April 2022 to March 2024

Examination of Factors Influencing Mental Health and Suicidality

CANSSI Ontario

We aim to examine the risk and protective factors influencing suicidal ideation and related mental health phenotypes in the CanPath dataset

Other faculty contributors

Co-Principal Investigators: Wei Xu, Pratyusha Attaluri, Arun K. Tiwari, Gwyneth Zai, James Kennedy

Total funding (Direct costs): $5,000

2022-2023

Using Long-read Whole-genome Sequencing to Understand Treatment Resistance in Psychiatric Patients

McLaughlin Centre

We aim to conduct a long-read whole-genome sequencing study to examine genetic factors of treatment resistance in diverse psychiatric populations.

Other faculty contributors

Co-Principal Investigators: James L. Kennedy, Arun K. Tiwari, Gwyneth C. Zai, Joyce So, Jerry Warsh

Total funding (Direct costs): $75,000

2022-2023